Starting at: $82.00
| SKU | Package Size | Price | Quantity | Add to Cart |
|---|---|---|---|---|
| IX03010-25 | 25ug | Starting at: $199.00 | ||
| IX03010-5 | 5ug | Starting at: $82.00 |
Starting at: $699.00
Starting at: $1,012.00
Overview
| Synonyms | Macrophage Colony Stimulating Factor, MGI-IM,CSF1, CSF-1, MCSF |
| Description | Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages[1]. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells [2]. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers [1][3][4]. |
| Accession No | NP_076471.3 |
| Species | Rat |
| Source | CHO |
| Biological Activity | ED50 < 2.5 ng/ml, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 4×105 units/mg. |
| Sequence |
EVSEHCSHMI GNGHLQILQQ LIDSQMETAC LIEYKFVDQE
QLDDPVCYLK KAFVLVQVII EETMRFKDNT PNANATERLQ ELSMKLNSCF IKDYKEQNEA CVQTYKESPL RLLEKIKNFF NETKNFLEKD WNIFSKNCND SLAKCSSRDV VTKP |
Properties
| Measured Molecular Weight | 32-40 kDa, observed by non-reducing SDS-PAGE. |
| Purity | > 95% as analyzed by SDS-PAGE. |
| Formulation | Lyophilized after extensive dialysis against PBS. |
| Reconstitution | Reconstituted in ddH2O or PBS at 100 μg/ml. |
| Endotoxin Level | < 0.2 EU/μg, determined by LAL method. |
| Storage | Lyophilized recombinant Rat Macrophage-Colony Stimulating Factor (M-CSF) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rrM-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
| Note | For research use only |