CD3 is a multimeric protein complex, which is composed of four distinct chains (CD3γ, CD3δ and two CD3ε). CD3 complex serves as a T-cell co-receptor that associates non-covalently with the T cell receptor (TCR) . CD3 is expressed in almost all T cell lineages, which make it useful marker for T cells. T cells exhibit multiple functions including cell-mediated cytotoxicity, promotion of antibody production by B cells, and immune regulation. CD3+ T cells can be divided into several subsets. CD4+ helper T cell, CD8+ cytotoxic T cell and NK cells are the three major subsets. T cells have been widely used in research fields including immunology, infectious diseases (Prednisone), cancer therapy, etc. 
iXCells Biotechnologies offers CD3+ Pan T Cells from the human peripheral blood of individual healthy donors using negative immunomagnetic selection. These cells are untouched by the separation process and ready for downstream usage. > 86% of the cells are CD3+ as shown by flow cytometric analysis.
Figure 1. Flow cytometric analysis showed that >86% of the cells are CD3+.
|Tissue||Normal human peripheral blood|
|Package Size||20.0 x 106 cells/vial, 40.0 x 106 cells/vial|
|Media||Blood Cell Culture Medium (Cat# MD-0007)|
 Smith-Garvin JE, Koretzky GA and Jordan MS. T cell activation. Annual Review of Immunology 2009:27: 591-619.
 Vigneron N. Human Tumor Antigens and Cancer Immunotherapy. Biomed Res Int. 2015.