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Human Peripheral Blood CD8+ Cytotoxic T Cells (Positive Selection)

SKU: 10HU-024

Human Peripheral Blood CD8+ Cytotoxic T Cells (Positive Selection)

SKU: 10HU-024
Pricing Starting at

Starting at: $644.00

Available Options

SKUPackage SizePriceQuantityAdd to Cart
10HU-024-5MCryopreserved, 5.0 million cells/vialStarting at: $644.00
10HU-024-10MCryopreserved, 10 million cells/vialStarting at: $937.00

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Product Description

The CD8+ T cells, also known as Cytotoxic T cells (TC cells), are a type of T cells that kill cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways. Most cytotoxic T cells express T-cell receptors (TCRs) that can recognize a specific antigen, and a glycoprotein called CD8 which binds to the constant portion of the class I MHC molecule. When exposed to infected/dysfunctional somatic cells, CD8+ T cells release the cytotoxins perforin, granzymes, and granulysin, which triggers the caspase cascade and eventually leads to apoptosis. CD8+ T cells have been implicated in the pathogenesis of hepatitis B virus infection [1], arthritis [2] etc.

iXCells Biotechnologies offers CD8+ T cells isolated from normal human peripheral blood mononuclear cells (PBMCs) using positive immunomagnetic selection. > 90% of the cells are CD8+ as showed by flow cytometric analysis (Figure 1).

Figure 1. Flow cytometric analysis showed that >90% of the cells are CD8+.

Product Details

issue Normal human peripheral blood
Package Size 5.0×106 cells/vial, 1.0×107 cells/vial
Purity >90%
Passage Number P0
Shipped Cryopreserved
Storage Liquid nitrogen
Growth Properties Suspension
Media Blood Cell Culture Medium (Cat# MD-0007)


[1] Iannacone, Matteo; Sitia, Giovanni; Guidotti, Luca G (2006). “Pathogenetic and antiviral immune responses against hepatitis B virus”. Future Virology 1 (2): 189–96.

[2] Subramanian S and Ramalingam K (2005). “Electron microscopic evidence on the participation Cytotoxic T Lymphocytes and Macrophages in Mtb adjuvant induced connective tissue inflammation and arthritogenesis in Rattus norvegicus”. Asian Journal of Microbiology, Biotechnology and Environmental Sciences 7 (2): 227–233.

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Manuals & Protocols

  • Hyun, S. Y., Na, E. J., Jang, J. E., Chung, H., Kim, S. J., Kim, J. S., . . . Cheong, J. (2020). Immunosuppressive role of cd11b + cd33 + Hladr myeloid‐derived suppressor CELLS‐LIKE BLAST subpopulation in acute myeloid leukemia. Cancer Medicine, 9(19), 7007-7017. doi:10.1002/cam4.3360 -- Learn More