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Human Renal Fibroblasts

SKU: 10HU-238

Human Renal Fibroblasts

SKU: 10HU-238
Pricing Starting at

Starting at: $680.00

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10HU-238Cryopreserved, 0.5 million cells/vialStarting at: $680.00

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Product Description

Fibroblasts and myofibroblasts are believed to be the key effector cells in renal fibrogenesis responsible for the synthesis and deposition of extracellular matrix components [1]. Although fibroblasts are histologically visible in normal kidneys, there are relatively few of them and proximal tubular epithelial cells predominate. In progressive disease, however, the interstitium becomes filled with myofibroblasts [2]. Fibroblasts are considered the primary matrix-producing cells in the kidney and hence they are clinically relevant as principal mediators of renal fibrosis associated with progressive renal failure [3].

iXCells Biotechnologies provides high quality Human Renal Fibroblasts, which are isolated from adult human lung tissue and cryopreserved at P1, with >0.5 million cells in each vial. Human Renal Fibroblasts express fibronectin and are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can further expand no more than 3 passages in Fibroblast Growth Medium (Cat# MD-0011) under the condition suggested by iXCells Biotechnologies.


Human Renal Fibroblasts

Figure 1. Human Renal Fibroblasts. (A) Phase contrast image. (B) Immunofluorescence staining with antibodies against Vimentin.


Product Details

Tissue Normal human kidney tissue
Package Size 0.5 million cells/vial
Passage Number P1
Shipped Cryopreserved
Storage Liquid nitrogen
Growth Properties Adherent
Media Fibroblast Growth Medium (Cat# MD-0011)



[1] Soma Meran and Robert Steadman (2011) “Fibroblasts and myofibroblasts in renal fibrosis”. Int. J. Exp. Path. 92: 158–167

[2] H. Terence Cook. (2010) “The Origin of Renal Fibroblasts and Progression of Kidney Disease”. The American Journal of Pathology, 176 (1):22-24.

[3] Frank Strutz and Michael Zeisberg. (2002) “Renal Fibroblasts and Myofibroblasts in Chronic Kidney Disease”. JASN, 17: 2992-2998.


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