GABAergic Neuron Culture Medium

SKU	Package Size	Price	Quantity	Add to Cart
MD-0122-100mL	100 ML	Starting at: $329.00	GABAergic Neuron Culture Medium quantity

Description

Product Description

GABAergic neurons are a type of neuron that produce gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits nerve transmission and reduces neuronal excitability mainly in hippocampus, thalamus, basal ganglia, hypothalamus, and brainstem ^[1]. The balance between inhibitory neuronal transmission via GABA and excitatory neuronal transmission via glutamate is essential for proper cell membrane stability and neurologic function in central nervous system (CNS). In GABAergic neurons, GABA is primarily synthesized from glutamate, a process catalyzed by glutamate decarboxylase (GAD). GAD, especially the CNS specific 67 kDa subtype GAD67, as well as vesicular GABA neurotransmitter transporter (vGAT) are commonly used cell specific markers for GABAergic neurons ^[2].

iXCells^®GABAergic Neuron Culture Medium is a complete medium uniquely designed to maintain GABAergic neuron growth in vitro and their functions, as measured by the expression of the cell type specific markers along with the electrophysiology activities. The medium is provided as the antibiotics free complete culture medium. No extra glutamine is needed for cell culture.

Product Details

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SKU

MD-0122

Country of manufacture

United States of America (USA)

Quantity

One Bottle

Form

Liquid

Component, Package and Storage

Component	Name	Size	Shipping	Storage
MD-0122	GABAergic Neuron Culture Medium	100 mL	Dry ice	-20°C

Note: Please store the medium immediately at -20°C upon arrival.

Sterility Test

Negative for bacteria, yeast, fungi, and mycoplasma.

Product line

Mammalian cells
iPS cells and derivatives
Serum free
With phenol red
Antibiotics free

Product use

Do not use components that are beyond the expiration date indicated on the label.
Tested in the iXCells Human Cortical GABAergic Neurons 2.0 (Cat: 40HU-022) following the recommended protocol in a 37°C, 5% CO2 incubator.
For laboratory research use only. Not for use in diagnostic procedures.
Results may vary due to variations among tissue origin or donors.
Results may vary due to different culture conditions including temperature, CO2 concentration, culture vessels, coating conditions, medium adding amount, and medium change frequency. For certain culture or test conditions, please follow the culture protocol for each specific cell type.
It is not approved for human or animal use.
iXCells in-house cell culture test was performed under antibiotics-free condition for ≥3 days by following the recommended protocol, and no bacterial or fungi contamination were observed during the culture period.
Optional: Antibiotics-Antimycotic (Fisher, Cat# 15240062) or Penicillin Streptomycin (Thermo Fisher, Cat# 15140122) at working solution could be added if necessary, which have been tested in-house without visible effect on cell morphology or function.

Precaution

When handling biohazardous materials such as cryopreserved cells, safe laboratory procedures should be followed, and personal protective equipment should be worn including but not limited to face masks, gloves, and lab coat.

Datasheet

Fully supplemented medium: No extra glutamine or antibiotics is needed for cell culture.
Serum free/ Animal origin free: More defined cell culture process.
Long-Term Culturing Viability: Under optimized condition with iXCells^®GABAergic Neuron Culture Medium, the GABAergic neurons can be cultured for extended periods of time, maintaining their functionality and morphology for up to 40 days.