Starting at: $986.00
| SKU | Package Size | Price | Quantity | Add to Cart |
|---|---|---|---|---|
| 10HU-240-0.5M | Cryopreserved, 0.5 million cells/vial | Starting at: $986.00 |
Starting at: $986.00
Starting at: $739.00
Product Description
Fibroblasts, one of the most abundant cell types, are morphologically and functionally heterogeneous [1]. Human pulmonary fibroblasts (HPF) play an important role in maintaining the structural integrity of connective tissue and in the synthesis of extracellular matrix proteins such as collagens and glycoproteins [2]. Under pathological conditions, such as tissue injury, HPF are stimulated to take part in the process of airway inflammation and airway remodeling which might directly or indirectly lead to angiogenesis, idiopathic fibrosis or even cancer [3]. Idiopathic pulmonary fibrosis (IPF) is a rare, progressive illness of the respiratory system, characterized by replacement of healthy lung tissue with altered extracellular matrix and alveolar architecture is destroyed. IPF is believed to be the result of an aberrant wound healing process involving abnormal fibroblasts activation [4].
iXCells Biotechnologies provides high quality HPF, which are isolated from lung tissue of IPF patients. It provides a robust model for in vitro studies of IPF as well as other fibroblasts related diseases. HPF from iXCells Biotechnologies are cryopreserved at P2, with >0.5 million cells in each vial. HPF express Fibronectin and Vimentin. They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi and can further expand for 10 population doublings in Fibroblast Growth Medium (Cat# MD-0011) under the condition suggested by iXCells Biotechnologies.
Figure 1. Human Pulmonary Fibroblasts (HPF, Idiopathic Pulmonary Fibrosis). The cells were recovered, and seeded at 10,000 cells/cm2 following iXCells’ protocol. Phase contrast images were taken at the indicated time post recovery.
Figure 2. Immunofluorescence staining of Human Pulmonary Fibroblasts (HPF, Idiopathic Pulmonary Fibrosis) with antibodies against Fibronectin (Red) and Vimentin (Green). Nuclei were counterstained by DAPI (Blue).
Product Details
| Tissue | Human lung tissue |
| Package Size | 0.5 million cells/vial |
| Passage Number | P2 |
| Shipped | Cryopreserved |
| Storage | Liquid nitrogen |
| Growth Properties | Adherent |
| Media | Fibroblast Growth Medium(Cat# MD-0011) |
Starting at: $986.00
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Starting at: $986.00