Adipose Tissue Derived Cells

Adipose tissue, or body fat, is loose connective tissue composed mostly of adipocytes. In addition to adipocytes, adipose tissue contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells (i.e., adipose tissue macrophages) [1] (Figure 1). Adipose tissue is derived from preadipocytes. Its main role is to store energy in the form of lipids, although it also cushions and insulates the body. Far from hormonally inert, adipose tissue has, in recent years, been recognized as a major endocrine organ [2], as it produces hormones such as leptin, estrogen, resistin, and the cytokine TNFα. Moreover, adipose tissue can affect other organ systems of the body and may lead to disease. The two types of adipose tissue are white adipose tissue (WAT), which stores energy, and brown adipose tissue (BAT), which generates body heat.

iXCells offers a wide collection of primary cells isolated from human and rodent adipose tissues, including Stromal Vascular Fraction (SVF), Adipose-Derived Stem Cells (ADSCs), Preadipocytes (PAds). These cells are are fully validated by marker staining, flow cytometric analysis and differentiation.  They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.