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IL-2, Human

SKU: IX03074

IL-2, Human

SKU: IX03074
Pricing Starting at

Starting at: $88.00

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IX03074-11mgStarting at: $1,330.00
IX03074-1010ugStarting at: $88.00
IX03074-5050ugStarting at: $114.00

Associated Products

Description

Overview

Synonyms T-cell growth factor (TCGF), Aldesleukin
Description Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Accession No P60568
Species Human
Source HEK 293
Biological Activity ED50 < 2ng/ml, measured in a cell proliferation assay using CTLL-2 cells.
Sequence
00001   APTSSSTKKT   QLQLEHLLLD   LQMILNGINN   YKNPKLTRML
00041   TFKFYMPKKA   TELKHLQCLE   EELKPLEEVL   NLAQSKNFHL
00081   RPRDLISNIN   VIVLELKGSE   TTFMCEYADE   TATIVEFLNR
00121   WITFCQSIIS   TLT

Properties

Measured Molecular Weight 15~16 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Human Interleukin-2 (IL-2) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human Interleukin-2 (IL-2) should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only

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